Anastrozol is a non-steroidal aromatase inhibitor primarily used in the treatment of hormone-receptor-positive breast cancer in postmenopausal women. By inhibiting the aromatase enzyme, Anastrozol decreases estrogen levels in the body, which is crucial in cases where estrogen can promote the growth of cancerous cells. Understanding the effects of Anastrozol can help patients and healthcare providers make informed decisions regarding breast cancer treatment.

On the https://gaelicsupps.com/categories/oestrogenblocker-aromatasehemmer/anastrozol/ website you will find everything you need to know about Anastrozol, from indications to dosage regimens.

1. Indications for Anastrozol

Anastrozol is indicated for:

  • Adjuvant treatment of hormone-receptor-positive breast cancer in postmenopausal women.
  • Treatment of advanced breast cancer in postmenopausal women whose disease has progressed following tamoxifen therapy.
  • Reduction of the risk of developing breast cancer in women at high risk.

2. Mechanism of Action

Anastrozol works by:

  • Inhibiting the aromatase enzyme, which is responsible for converting androgens into estrogens.
  • Leading to a significant reduction in circulating estrogen levels in the body.
  • Effectively starving estrogen-dependent tumors, thereby inhibiting their growth and progression.

3. Dosage and Administration

The typical dosage of Anastrozol is:

  • One 1 mg tablet taken orally once daily, with or without food.
  • Long-term treatment can be essential, often taken for 5 years after surgery or other therapies.

4. Potential Side Effects

Common side effects include:

  • Hot flashes
  • Joint pain or stiffness
  • Fatigue
  • Risk of osteoporosis due to decreased estrogen levels.

5. Conclusion

Anastrozol has revolutionized the treatment of hormone-receptor-positive breast cancer, providing an effective option for postmenopausal women. By understanding its effects, indications, and potential side effects, patients can engage more actively in their treatment decisions in partnership with their healthcare providers.